Head
Senior Advisor
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We focus on the study of the altered oxide-reductive balance, that influences protein folding and calcium homeostasis, inducing deterioration of muscle cells.
More specifically, we analyse the role of SEPN1 protein, whose alterations generate a rare myopathy. We study the association between modifications in SEPN1 andendoplasmic reticulum stress. The ultimate aim is the development of a pharmacological strategy for the treatment of SEPN1-related myopathy.
This laboratory also investigates how the endoplasmic reticulum stress affects the aggressiveness of different tumors to suggest some useful targets for the development of effective cancer therapies.
RESEARCH AREAS
Study of SEPN1 function, a protein associated with a rare myopathy
Development of a pharmacological strategy for the treatment of SEPN1-related myopathy
Study of the connection between endoplasmic reticulum stress and tumor aggressiveness
Head Unit
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Staff
Codice:
International Consensus on Cardiopulmonary Resuscitation.
1205
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Head
Senior Advisor
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